To study the role of serum lactate dehydrogenase in prediction of adverse outcomes of pre-eclampsia and eclampsia

Abstract

The present study was carried out in the Department of Obstetrics and Gynaecology, with an aim to study the role of Serum Lactate Dehydrogenase in prediction of adverse outcomes of pre-eclampsia and eclampsia. The patients were selected from patients who were admitted to as emergency cases in labour room patients were irrespective of age and parity. On a specially designed proforma for this study, the patient particulars like detailed obstetric history, examination and laboratory findings were studied.Among the cases studied 76% preeclampsia and 96% eclampsia patient were unbooked case and most of them resided in rural areas while the remaining were from urban slums. Hyperbilirubinemia was seen in small groups of pre-eclampsia and eclampsia patients. Deranged level of liver enzyme were also found in small group of pre-eclampsia and eclampsia patients. LDH level was found significant higher (more than 600 IU/L) in pre-eclampsia and eclampsia patients. Eclampsia is associated with significant maternal and perinatal morbidity and mortality. The higher mortality is due to high percentage of the patient being unbooked and majority received no therapeutic intervention until admission. Among the cases studied 76% preeclampsia and 96% eclampsia patient were unbooked case and most of them resided in rural areas while the remaining were from urban slums. Hyperbilirubinemia was seen in small groups of pre-eclampsia and eclampsia patients. Deranged level of liver enzyme were also found in small group of pre-eclampsia and eclampsia patients. LDH level was found significant higher (more than 600 IU/L) in pre-eclampsia and eclampsia patients.