TO STUDY THE EFFICACY OF PROPHYLACTIC INTRAVENOUS PHENYLEPHRINE IN PROPOFOL-INDUCED HYPOTENSION DURING INDUCTION OF GENERALANAESTHESIA

Abstract

INTRODUCTION :Hypotension is the most common complication during induction of general anesthesia. Hypotension is the decrease in systolic blood pressure below the normal accepted value, that is less than 90mm of Hg or decrease in mean arterial pressure of less than 65 mmHg. It is asymptomatic while induction of anesthesia and recognition requires proper predictors on multipara monitors like systolic blood pressure and mean arterial blood pressure. To prevent hypotension many methods like co-loading with intravenous crystalloids, vasopressors have been tried. In our study we are using prophylactic intravenous phenylephrine to prevent fall in blood pressure and to measure the SBPand MAPafter induction of anaesthesia and intubation in the study and control group. (At 5 minutes, 10 minutes, and 15 minutes)” METHODOLOGY-The study was conducted at “Dr. D. Y. Patil medical college, hospital, and research institute” from March 2021 to August 2022 after institutional ethical approval. Total of 120 patients were selected and were divided into two groups, the study group (n =60) the control group (n =60). Routine systematic preoperative assessment and investigation were performed according to the study protocol. RESULTS- SBP was observed to be signicantly declined in the “control group” compared to the “study group” when observed at 10min and 15min time intervals. MAPwas found to be effectively reduced in the “control group compared to the “study group” when observed at 10 min and 15min time intervals. CONCLUSION-From the study it was concluded that the “prophylactic intravenous phenylephrine is effective in preventing fall in blood pressure associated with propofolinduced hypotension at the time of induction during general anaesthesia”