Abstract

Background: The Human Immunodeficiency Virus (HIV) is a lenti virus (a subgroup of retrovirus) that causes HIV infection and acquired immunodeficiency syndrome (AIDS).1 HIV causes progressive impairment in body’s immune system leading to increased susceptibility to tumours and fatal opportunistic infection known as acquired immune-deficiency syndrome (AIDS). The aim of our study was to study the clinical profile of HIV/AIDS patients.
 Methods: It was an observational study including 100 HIV positive patients who were willing to be a part of the study. According to the WHO case definition, HIV in adults and children 18 months or older is diagnosed based on positive HIV antibody testing (rapid or laboratory-based enzyme immunoassay).
 Results: In this study Fever was the predominant symptom seen in 75% of cases; followed by weight loss (55%), Cough with expectorants (36%), Haemoptysis (35%), long fever (34%).
 Conclusion: The present study found that most of the HIV infected patients were from sexually active age group. Emphasizing the need to strengthen our Information education and communication (IEC) strategies to contain HIV/AIDS.
 Keywords: Acquired Immuno Deficiency Syndrome (AIDS), Hematological manifestations, Clinical profile.

Highlights

  • Haematological abnormalities are common findings in patients infected by Human Immunodeficiency Virus (HIV) virus

  • In this study Fever was the predominant symptom seen in 75% of cases; followed by weight loss (55%), Cough with expectorants (36%), Haemoptysis (35%), long fever (34%)

  • The present study found that most of the HIV infected patients were from sexually active age group

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Summary

Introduction

Haematological abnormalities are common findings in patients infected by HIV virus. The common findings include anemia, leukopenia thrombocytopenia or pancytopenia. These abnormalities may be attributable to the direct cytotoxic effect of the virus on progenitor cells, ineffective hematopoiesis, opportunistic infections immune mechanisms and drug reactions.[1]. Anemia is a very common finding in HIV infected patients in individuals with more advanced disease HIV infection alone without other complicating illness can produce anemia in some patients. The aim of our study was to study the clinical profile of HIV/AIDS patients. Methods: It was an observational study including 100 HIV positive patients who were willing to be a part of the study.

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