Abstract

Background: Pancreatitis is an inflammatory condition that affects the pancreas and may also affect other tissues or distant organ. In this study our aim is to see if blood calcium level can be used as a prognostic marker in determining the severity of acute pancreatitis because hypocalcaemia is linked to higher mortality and hospitalization.
 Method: A retrospective study was conducted in the medical records department of a tertiary care health facility. A total of 75 participants were included in the research. .demographic details of all patients were collected .Patients above 18 years who presented with of epigastric pain, pre-Diagnosed gallstones, alcoholism were included int this study. The lowest total calcium levels were collected in order to examine total calcium as a predictive factor for severity. All of these information were collected and analyzed to get the appropriate findings.
 Results: A total of 75 patients were included in the research. The age of patients in each severity grade did not differ significantly (p value>0.05). The gender distribution of the two groups did not differ. (P >0.05). For mild and severe acute pancreatitis, mean total calcium levels were 7.98 and 6.67, respectively, which was statistically significant (p< 0.05).
 Conclusion: The total serum calcium level is a useful indicator for assessing pancreatitis.

Highlights

  • Pancreatitis is an inflammatory condition that affects the pancreas and may affect other tissues or distant organ system [1,2,3]

  • The severity of pancreatitis is assessed using Ranson criteria, with total calcium levels used as a prognostic marker because severe hypocalcemia is linked to higher mortality and hospitalization [6]

  • The data analysis was done using Ranson criteria and sensitivity(S), specificity(SP), positive predictive value(PPV),negative predictive value (NPV) for serum calcium was calculated at various cut off levels of hypocalcemia

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Summary

Introduction

Pancreatitis is an inflammatory condition that affects the pancreas and may affect other tissues or distant organ system [1,2,3] It manifests in both acute and chronic forms. The severity of pancreatitis is assessed using Ranson criteria, with total calcium levels used as a prognostic marker because severe hypocalcemia is linked to higher mortality and hospitalization [6]. In this study our aim is to see if blood calcium level can be used as a prognostic marker in determining the severity of acute pancreatitis because hypocalcaemia is linked to higher mortality and hospitalization. The lowest total calcium levels were collected in order to examine total calcium as a predictive factor for severity. Conclusion: The total serum calcium level is a useful indicator for assessing pancreatitis

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