Abstract

Background: Respiratory failure is a condition in which the respiratory system fails in one or both of its gas-exchanging functions- oxygenation of pulmonary arterial blood and carbon dioxide elimination from mixed venous blood. NIV is used as a replacement for invasive ventilation in a few conditions, and its exibility also allows it to be a valuable component in patient management. Its use in acute respiratory failure is well accepted and widespread. AIM: This study was conducted to study various parameters such as baseline PCO2 levels, pH, PO2 levels, Heart rate, respiratory rate, and their correlation with the outcome of Non-invasive Ventilation. This is a prospective observational studyMethods: conducted on 100 patients admitted with either Type-I or Type -II respiratory failure. Results: Respiratory rate <30, Heart rate <130, PCO2 45-70 are associated with good outcomes of Non-invasive ventilation. Type of respiratory failure, sputum aerobic culture are not predictors of NIV outcomes. NIV in acute respiratory failure, irrespective of the type of respiratoryConclusion: failure helps in improving gas exchange, reduces intubation and length of hospital stay hence, its use as the rst modality of treatment in patients without overt contraindications is recommended. Overall, NIV is safe and effective in patients with acute respiratory failure as there are no major complications associated with its use.

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