Abstract
ABSTRACT.This article reviews the complex and increasingly scrutinized relationship between sleep and epilepsy, emphasizing the differential activation of interictal epileptiform discharges and seizures during different sleep stages, the sleep-related epilepsies (those with preferential occurrence during sleep or following arousal), and sleep disorders that may exacerbate or mimic epilepsy. Recognition and treatment of nocturnal seizures and primary sleep disorders in patients with epilepsy may lead to improvements in seizure burden and quality of life.
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