To investigate phytochemical parameter, Pharmacognostical evaluation, pharmacological (anti-bacterial) activity of the extract of Euphorbia pulcherrima

Abstract

Introduction: Euphorbia pulcherrima is member of Euphorbiaceae family of medicinal plants, and it is used to cure variety of ailments which includes toothache, vomiting, fractures, severe bleeding, bruising, and hypermenorrhoea. Euphorbia pulcherrima has been found to possess a variety of chemicals, including alkaloids, steroids, terpenoids, flavonoids and reducing sugars. The review analyses its pharmacological profile, chemical component, and phytochemistry, with an emphasis on antioxidant activity, antimicrobial activity, Osteoclast activity, analgesic activity, anti-inflammatory activity, sedative activity, muscle relaxant activity, anticonvulsant activity and toxicological profile, in order to better assess the plants medicinal potential. Traditionally the latex has been employed as an anti-vomiting and toothache treatment. Aches and pains have been treated with leaf poultices. In traditional Chinese medicine it has been used it to treat fractures, severe bleeding, bruising, and hypermenorrhoea. 
 Methods: Due to extensive research on the pharmacological effects and active compounds of Euphorbia pulcherrima, it has a great deal of potential in modern medicine. Phyto, physicochemical standardization of dried, matured root of Euphorbia pulcherrima has been carried out in the present study. The study includes organoleptic characters along with estimation of its physicochemical parameters such as loss on drying, ash values, extractability in water and methanol. Preliminary phytochemical screening and anti-bacterial assay has been conducted.
 Conclusion: As there is not enough evidence for detailed physicochemical and phytochemical evaluation on root of Euphorbia pulcherrima is reported. The present study reveals that the selected plant extract produces antimicrobial activity with dose dependent manner. However, it needs further evaluation in clinical settings before consideration for the treatment of different diseases.
 Keywords: Euphorbia pulcherrima, Phytochemicals, pharmacological activity, Physicochemical.