Abstract

Background & Method: The study was conducted in the Department of Medicine Shyam Shah Medical College and Associated Sanjay Gandhi Memorial Hospital, Rewa (M.P). History was followed by a careful clinical examination i.e. cardiovascular, respiratory and gastrointestinal and nervous system. Investigations had done included routine haematological examination, Biochemical analysis, urine examination, ECG, 2 D. Echo & Histopathological examination was done.
 Result: ST-T changes were most common finding in Aluminium phosphide poisoning in relation to mortality. However hyperkalemia was the most ominous finding associated with 100% mortality, ECG finding in EDB was normal ECG. The most ominous finding was arrhythmia which was associated with 100% mortality. Survivors of ethylene dibromide poisoning echocardiography was normal in 11 (84.61%) followed by pericardial effusion in 2 (15.38%) patients.
 Conclusion: Noteworthy finding was absence of correlation between cardiovascular involvement, histopathological changes and ECG findings. It was seen that even if ECG showed normal pattern there were significant histopathological changes in heart.
 Keywords: electro-cardiographic, Aluminium phosphide, ethylene dibromide & poisoning.

Highlights

  • Hyperkalemia was the most ominous finding associated with 100% mortality, ECG finding in EDB was normal ECG

  • The most ominous finding was arrhythmia which was associated with 100% mortality

  • Poisoning refers to the development of dose-related adverse effect following exposure to these substances (Linden & Burns 2001)[1], A pesticide is usually defined as a chemical substance, biological agent, antimicrobial or disinfectant used against pests including insects, plant pathogens, weeds, molluscs, birds, mammals, fish, nematodes and microbes that compete with humans for food, destroy property, have a propensity for spreading or a vector for disease or a nuisance (Goel & Aggarwal 2007) [2]

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Summary

Introduction

Poison is a substance (solid, liquid or gaseous), which if introduced in the living body, or brought into contact with any part thereof, will produce ill health or death, by its constitutional or local effects or both. The term pesticide has a broader connotation and includes herbicides, rodenticides, fumigants, nematocides, algaecides, ascaricides, molluscicides, disinfectants, defoliants and fungicides (Goel & Aggarwal 2007)[2] Acute poisoning with pesticides is a global public health Problem and accounts for as many as 3 lack deaths, Worldwide every year. There was sort of epidemic of Aluminium Phosphide poisoning in northern India in 1987, considered even worse than the Bhopal gas tragedy of 1984. It may be the tip of an iceberg as large number of cases of Aluminium Phosphide does not come for treatment (Bajaj et al 1990)[5]

Material & Method
Haematological Examination: Total Leucocytes Count
Results
Discussion
Full Text
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