Abstract

Objective: Decreased serum magnesium and ascorbic acid has been associated with increased risk of myocardial infarction (MI). The present study was planned to evaluate the status of ascorbic acid in patients suffering from MI and to compare them with normal healthy individuals. Methods: This retrospective study was conducted in the Department of Biochemistry in collaboration with the Department of Medicine, Government Medical College, Guru Nanak Dev Hospital, Amritsar. Fifty patients already diagnosed with MI, attending medicine OPD and IPD. Fifty healthy individuals with ages and sex-matched from the same population served as controls. Plasma acorbic acid levels and lipid profiles were also estimated. Result: In our study, we observed that the difference between the plasma ascorbic acid levels of normal individuals and the patient of MI was statistically highly significant (p<0.001). It was also seen that the maximum number of subjects was found the age of 51–70 years in MI patients. Conclusion: Decreased plasma ascorbic acid levels may be one of the causes of MI, so its supplementation may delay MI and its complications.

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