Abstract

Background: Patients with RA have higher rates of morbidities and mortalities than in general population, which is highly attributed to an increased risk of CVD among RA patients and often untreated, leading to a decrease in life expectancy. Owing to its high prevalence and prognostic importance, professional societies and experts groups have increasingly emphasized the importance of CVD prevention and prompt recognitions in patients hospitalized with RA. Objective: To evaluate the frequency of newly diagnosed ischemic heart diseases in RA patients. Methods: It was a hospital based cross- sectional study. Study was conducted at Medicine Department of Chittagong Medical College Hospital (CMCH) for six months period from July’2018 to December’2018. A total 58 diagnosed RA case were selected purposively from both outdoor and indoor of Medicine Department of CMCH. Those having different comorbid condition like stroke, heart failure, chronic kidney disease, diabetes, pregnancy, encephalopathy, bleeding disorder, hypothyroidism, hyperthyroidism or unwilling to be included in the study were excluded. Patients’ demographics, serology results including rheumatoid factor (RF), anti-cyclic citrullinated peptide antibody (anti-CCP) and antinuclear antibody (ANA), as well as, disease activity score in 28 joints (DAS28) were recorded in a case record form. Results: Percentage of the patients newly diagnosed as hypertensive and diabetic were 8.6% and 5.2% respectively. RA patients with IHD were 14%, had prolonged disease duration 3.56 ± 2.16 and high disease activity 27.6%. Percentages of patients had hypercholesterolemia, low high density lipoprotein (HDL), High Low density lipoprotein (LDL) were 81%, 98.3% and 100% respectively. Conclusion: Proportions of the patients were newly diagnosed as hypertensive and diabetic were 8.6% and 5.2% respectively. RA patients with IHD were more aged, had prolonged disease duration and high disease activity.

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