TO EVALUATE AND COMPARE THE EFFECTS OF PERIOPERATIVE INFUSION OF 2% LIGNOCAINE VERSUS DEXMEDETOMIDINE ON POSTOPERATIVE PAIN AND QUALITY OF RECOVERY IN PATIENTS UNDERGOING LAPAROSCOPIC SURGERIES UNDER GENERAL ANESTHESIA

Abstract

Background: It is important to have good postoperative pain control and early recovery after laparoscopic surgeries. Intravenous 2% lidocaine has anti-hyperalgesic, anti inammatory and analgesic effects while dexmedetomidine provides anti-nociception, analgesic, sedative and sympatholytic effects. This study aims to compare the effects of both these drugs in terms of postoperative pain and quality of recovery after laparoscopic surgeries. After obtaining approval of the hospital ethical commit Method: tee and informed consent, 80 patients were randomly allocated into two group of 40 each, In group L (Lidocaine group), patients received intravenous 2% lidocaine (preservative free) 1.5mg/kg bolus followed by an infusion of 2mg/kg/hr and in group D (dexmedetomidine group), patients were given 1mcg/kg dexmedetomidine bolus followed by an infusion of 0.5mcg/kg/hr. The postoperative, pain scores, time for rst request of rescue analgesia, total analgesic consumption and quality of recovery were recorded in both the groups. The mean VAS score over 24 hours, Time for rst Results: request of rescue analgesia, Total Postoperative Analgesic Consumption was similar in both the groups. The Quality of Recovery Score –the combined QoR score was higher in group D 196.60±1.22 compared to group L 195.58±1.44 which was statistically highly signicant (p=0.001) Perioperative infusions Conclusion: of dexmedetomidine and lidocaine were found to have a similar analgesic sparing effect. However, dexmedetomidine proved superior to lidocaine in the Quality of Recovery