Abstract

Sodium concentration in the body is controlled by osmoregulatory system, which regulate water intake and excretion. If this system fails and plasma sodium level stray outside its normal range (135-145mmol/L), the cells are exposed to hypotonic or hypertonic stress. Hyponatremia is one of the most common electrolyte imbalances, occurring in up to 20% of hospitalized patients. It is defined as a plasma sodium concentration lower than 135mmol/L, with severe hyponatremia being below 120mmol/L. The symptoms of hyponatremia vary, depending not only on the concentration of sodium, but also on the rate of lowering of natremia. Mild symptoms may include headaches, cognitive impairment, lethargy, nausea, and vomiting; however, the signs may be subtle, or it may be asymptomatic whatsoever. In severe hyponatremia consciousness disturbances, seizures, and coma are common. The most common cause of hyponatremia include vomiting and diarrhea, adrenal insufficiency, heart, liver and renal failure, syndrome of inappropriate antidiuretic hormone secretion (SIADH), cerebral salt wasting syndrome, osmotic diuresis, and hyperglycemia. One should not forget about overhydration as a potential reason of hyponatremia.

Highlights

  • Sodium concentration in the body is controlled by osmoregulatory system, which regulate water intake and excretion

  • Case of A Severe Hyponatremia Caused by Fluid Oversupply in A 2-Year-Old Child

  • It is defined as a plasma sodium concentration lower than 135mmol/L, with severe hyponatremia being below 120mmol/L

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Summary

Introduction

Sodium concentration in the body is controlled by osmoregulatory system, which regulate water intake and excretion. *Corresponding author: Agnieszka Zubkiewicz-Kucharska, Department of Pediatric Endocrinology and Diabetology, Wrocław Medical University, Poland Submission: December08, 2020 Published: January 25, 2021 Case of A Severe Hyponatremia Caused by Fluid Oversupply in A 2-Year-Old Child. Case of A Severe Hyponatremia Caused by Fluid

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