Abstract
The present study describes the impact on renal function of a modern starch used for resuscitation in the intensive care unit. The role of starch in renal dysfunction, the importance of the definition of acute kidney injury and acute renal failure, and hyperoncoticity are reviewed.
Highlights
The present study describes the impact on renal function of a modern starch used for resuscitation in the intensive care unit
Boussekey and colleagues’ study is similar to another that provided a snapshot view of fluid resuscitation in a host of European intensive care units [2]
Hydroxyethyl starch (HES) use was not associated with renal injury even when administered to patients with sepsis
Summary
The present study describes the impact on renal function of a modern starch used for resuscitation in the intensive care unit. HES use was not associated with renal injury even when administered to patients with sepsis. Resuscitation with only HES (as predominantly occurs in HES trials) will establish a hyperoncotic state and predictably lead to acute kidney injury (AKI) or acute renal failure (ARF) [6].
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