To determine the association of serum AMH levels with oocyte quality in infertile women who underwent controlled ovarian stimulation (COS) for IVF cycles

Abstract

There is well documented evidence showing a decline in female fertility with advanced age. This decline includes a significant reduction in the quantity as well as the quality of the oocyte available in the ovarian reserve. The present study was conducted to determine the association of serum AMH levels with oocyte quality in infertile women who underwent controlled ovarian stimulation (COS) for IVF cycles. The present retrospective study conducted in IVF Department of Nowrosjee Wadia Maternity Hospital for 10 months. Total 100 patients were included in the study. Serum AMH levels and number of antral follicle (on second day of menstrual cycle) on transvaginal sonography was done for all patients. Fertilization was checked followed by embryo quality. Statistical analysis was performed by ANOVA. Significance was attributed to events with a p<0.05. A Total 100 patients were studied. The patients were divided into five groups based on AMH levels; the groups had 0, 44, 20, 26 and 10 patients respectively. Age was found to be independent predictor of ovarian reserve. There was no significant difference between the groups in relation to BMI.