TO CORRELATE CLINICAL FEATURES WITH EEG FINDINGS AND NEUROIMAGING (MRI) ABNORMALITIES IN CHILDREN WITH SEIZURE DISORDER

Abstract

Objectives: To evaluate the ndings of EEG and MRI in childhood seizure disorder, and to determine correlation between clinical features, EEG ndings and neuroimaging (MRI) abnormalities in children with seizure disorder. Methods: The present study was carried out in the department of Pediatrics in active collaboration with department of Radiodiagnosis, Maharani Laxmi Bai Medical College, Jhansi over a period of one year from june 2019 to june 2020. Children of 1 month to 15 years of age attending in OPD for follow up or admitted in pediatric wards were selected for this study. All patients underwent EEG and MRI. Our study group comprised of 70 cases of epilepsy, Among which 45 were male and 25 were female. The correlation between MRI and EEG abnormal ndings was analyzed using chi-square test. Result: Out of 70 cases, 45 cases were male and 25 cases were female. 52.85% cases had generalized seizure and 47.14% cases had partial seizure. Out of 70 cases, 50 cases had structural lesions, 4 cases had metabolic problem, 9 cases had fever and 7 cases had idiopathic etiology. 57.14% cases had abnormal MRI ndings. MRI abnormality present was ventricular abnormalities (22.85%), white matter lesion (14.28%), brain stem and cerebellar abnormalities (11.42%), cortical lesion (grey matter) (8.57%), deep grey matter (7.14%) and miscellaneous (2.85%). Out of 70 cases 44 cases had EEG abnormality. Out of 70 cases, 13 had normal MRI with normal EEG, 17 had normal MRI with abnormal EEG, 13 had abnormal MRI with normal EEG and 27 had abnormal MRI with abnormal EEG. The correlation between abnormal EEG and abnormal MRI was statistically not signicant (p=0.35). Conclusion: Our study reveals that both EEG and MRI are important tools in diagnosis of epilepsy in children and MRI is specially important to diagnose structural lesions in symptomatic epilepsy. In our study no signicant correlation was found between abnormal EEG and abnormal MRI ndings