Abstract
Background: To compare the efficacy of single dose versus conventional (multiple doses) antibiotic use in laparoscopic cholecystectomy in terms of SSI
 Methods: This study was carried out in the department of General Surgery Indira Gandhi Medical College Shimla (H.P.) on patients admitted with radiologically proven cholelithiasis.
 Results: In SD group of patients out of 50 patients, 03 patients (6%) developed wound sepsis and in C group 02 patients (4%) developed wound sepsis. P value was 0.65 which is statistically insignificant.
 Conclusion: The wound sepsis wise difference in both groups was found insignificants.
 Keywords: Single dose, Conventional, Gallstone, Wound sepsis
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