TO COMPARE THE EFFECTS OF ROPIVACAINE(1.8mg/kg) WITH FENTANYL (50μg) AND ROPIVACAINE (1.8mg/kg) WITH CLONIDINE (75μg) FOR INTRAVENOUS REGIONAL ANAESTHESIA (IVRA) FOR UPPER LIMB AND LOWER LIMB SURGERIES

Abstract

Introduction: Intravenous Regional Anaesthesia (IVRA) is indicatedfor short surgical procedures of upper extremity(below elbow) and of lower extremity (below knee). The aim of this randomised double-blind controlled study was to investigate the effects of adding Injection Clonidine as adjuvant to Injection Ropivacaine and Injection Fentanyl as adjuvant to injection Ropivacaine for IVRA in patients undergoing upper limb (below elbow) and lower limb (below knee) surgeries. Sixty adult ASA I and II patients Material and methods: of either sex in the age range of 20 to 60 years were randomly divided equally into 2 groups of 30 each. Group A received Injection Ropivacaine(0.75%) 1.8 mg/kgwith Injection Clonidine75µg/kg and Group B received Injection Ropivacaine (0.75%) 1.8 mg/kg with Injection Fentanyl 50 µg/kg. Results: Sensory onset showed high statistically signicant difference with Group A having earlier onset at 28.50 19.96 seconds as compared to Group B at 238 111.95 seconds (P<0.0001). Comparison of peak sensory showed high signicant statistical difference with Group A having earlier onset at 194 223.21 seconds as compared to Group B at 720 217.19 seconds (P<0.0001). The sensory wearoff between both the groups were highly signicant statistically showing Group A at 1150 ± 486.19 seconds as compared with Group B 184 ± 112.45 seconds (P<0.0001). The Visual Analogue Score in post operative ward just after completion of surgery show Group B having higher VAS score as compared with Group A.The time for rescue analgesia was prolonged in Group A as compared with Group B. Conclusion: Adding Clonidine to Ropivacaine improved the quality of anaesthesia and post-operative analgesia in Intravenous Regional Anaesthesia as compared to when Fentanyl was added to Ropivacaine.