Abstract
This prospective study was done in the Department of Radiodiagnosis at M.G.M. Medical College, & M.Y. Hospital, Indore. A total of 40 patients who were referred to our department with strong clinical suspicion of renal lesion and those diagnosed by ultrasonography or contrast enhanced CT scan having a renal mass on either of them, were subjected to a non-contrast.
 ADC values are expressed in 10-3 mm2/s. DW imaging with ADC values allows differentiation of clear cell, papillary and chromophobe subtypes of RCCs, suggesting that DW imaging may be a useful tool in the preoperative characterization of RCC. Hence, MRI with DWI in particular is a very valuable non invasive tool for the Identification, characterization and differentiation of renal lesions.
 Study Designed: Observational Study.
 Keywords: DWI, Renal, Neoplams, ADC, Histopathological & Correlation.
Highlights
Diffusion is a physical property, which describes the microscopic random movement of molecules driven by their internal thermal energy
A total of 40 patients who were referred to our department with strong clinical suspicion of renal lesion and those diagnosed by ultrasonography or contrast enhanced CT scan having a renal mass on either of them, were subjected to a non-contrast
Apparent Diffusion Coefficient (ADC) values are expressed in 10-3 mm2/s
Summary
Diffusion is a physical property, which describes the microscopic random movement of (water) molecules driven by their internal thermal energy. This movement is known as Brownian motion. Intracellular water diffusion is more hindered than that in the extracellular spaces which are lacking natural barriers. Pathological processes which change the volume ratio or physical nature of intra- and extracellular spaces affect the diffusion of water molecules. Advances in MRI technique, Diffusion weighted imaging has been applied to renal examinations. Application of diffusion-weighted sequences in body imaging had been limited. Diffusion weighted MRI has an immense role in imaging renal masses. The Apparent Diffusion Coefficient (ADC) gives quantitative information in DW MRI and has been shown to be inversely related to cellularity and grade of neoplasms.[5,6,7] DW MRI can help in further characterization of renal mass lesions, in differentiating benign from malignant lesions and in subtyping of renal malignancies
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