Abstract
Background: To analyse the effect of endometrial scratching on pregnancy rates in previously failed IUI cycles
 Methods: Randomized control study conducted on Couples attending the Infertility Clinic, Obstetrics & Gynaecology Department, SMS Medical College, Jaipur and requiring repeat IUI were recruited for the study from Feb 2019 to November 2020.
 Results: women in which IUI failed two times positive results after scratching was present in 16.15% cases followed by 6.92% positive results in women who had three times IUI failed and women who had only one-time IUI failed positive results was present in 4.62% cases. In controls we found positive results with 5.38% in women having one-time IUI failed followed by 3.85% in women where two time IUI failed and only in 2.31% women positive results found having three time IUI failed.
 Conclusion: In conclusion this study demonstrates 2.5-3 fold increase in pregnancy rates after scratch, endometrial scratching can be a preferred option in patients with previous failed IUI cycles before opting for expensive IVF treatment.
 Keywords: IUI, IVF, Inferetility
Highlights
Infertility is the inability of a sexually active noncontracepting couple to achieve pregnancy in one year (WHO ICMART)
Background: To analyse the effect of endometrial scratching on pregnancy rates in previously failed IUI cycles Methods: Randomized control study conducted on Couples attending the Infertility Clinic, Obstetrics & Gynaecology Department, SMS Medical College, Jaipur and requiring repeat IUI were recruited for the study from Feb 2019 to November 2020
In controls we found positive results with 5.38% in women having one-time IUI failed followed by 3.85% in women where two time IUI failed and only in 2.31% women positive results found having three time IUI failed
Summary
Infertility is the inability of a sexually active noncontracepting couple to achieve pregnancy in one year (WHO ICMART). IUI is one of the most popular Assisted reproductive technique (ART) for treatment of unexplained infertility.[1]. Management options for unexplained infertility are expectant management, timed intercourse, IUI with or without controlled ovarian stimulation, ART, i.e. IVF/intracytoplasmic sperm injection (ICSI)[1]. For successful implantation there is a complex interaction between maternal endometrium and the conceptus. To analyse the effect of endometrial scratching on pregnancy rates in previously failed IUI cycles Methods: Randomized control study conducted on Couples attending the Infertility Clinic, Obstetrics & Gynaecology Department, SMS Medical College, Jaipur and requiring repeat IUI were recruited for the study from Feb 2019 to November 2020. Conclusion: In conclusion this study demonstrates 2.5-3 fold increase in pregnancy rates after scratch, endometrial scratching can be a preferred option in patients with previous failed IUI cycles before opting for expensive IVF treatment.
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