Abstract
Objectives: This study aims to evaluate the clinicopathological and nodal metastasis status of well-differentiated thyroid carcinoma in young people at Hanoi medical university Hospital. Participants and Methods: We conducted a prospective cohort study of 89 well-differentiated thyroid carcinoma patients under 40 years old treated by surgery at Hanoi medical university Hospital from September 2019 to May 2020. Results: The mean age was 32,35±5 and the ratio of female/male was 7,1/1. Most patients had a unilateral tumor with diameter ≤1cm (73,6%). 77,6% of tumors were classified as TIRADS 4 on ultrasound, and FNA gave malignant result in 70,2% of cases. Lymph node dissection was performed on 61,8% of patients. The overall rate of nodal metastasis was 40,5%. Central neck compartment nodal metastasis only was detected in 37,6% of cases, while 19,7% of patients had positive nodes in the lateral neck. The occult nodal metastasis rate was 29,8%. Nodal metastasis was significantly associated with the following factors: tumor size >1 cm,bilateral tumors and extrathyroidal extension (p<0.05). Conclusion: We found the overall rate of nodal metastasis was 40,5%, including central neck compartment nodal metastasis (37,6%), and 19,7% of patients had positive nodes in the lateral neck. The occult nodal metastasis rate was 29,8%. Keywords: well-differentiated thyroid carcinoma, young, nodal metastasis
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