TMulti-b-value diffusion weighted imaging combining dynamic enhanced time-signal strength curve in differential diagnosis of benign and malignant breast lesions

Abstract

Objective To explore the clinical application value of multi-b-value diffusion weighted imaging (mb-dwi) combining dynamic enhanced time-signal strength curve (TIC) in the differential diagnosis of benign and malignant breast lesions. Methods 236 patients taking breast MRI examination at our hospital from May 2016 to April 2017 were selected. Among which, 95 had malignant lesions and 141 benign. And 40 healthy volunteers were selected as a control group. All the three groups took MB-DWI examination; and TIC dispersion curve was drawn and post-processing was taken. The model parameters (ADC value) , ADCstandard, and TIC curve type of the three groups of diffuse weighted imaging (ADC) were observed. Results The ADC value and ADCstandard value were lower in the malignant lesion group than in the benign lesion group and the control group, with statistical differences (all P < 0.05) . The proportion of type I TIC curve was much lower in the malignant lesion group than in the benign lesion group and the control group, with statistical differences (P < 0.001) ; the proportion of type Ⅲ TIC curve was much higher in the malignant lesion group than in the benign lesion group and the control group, with statistical differences (P < 0.05) . Conclusion WB-DWI combined TIC curve can be used to diagnose benign and malignant lesions of mammary gland and has higher diagnostic value than only one indicator. Key words: Multi-b diffusion weighted imaging; Dynamic enhancement time-signal strength curve; Breast lesions; Differential diagnosis