Abstract
Recently developed rare earth ions doped NIR-NIR bioprobes, with excitation and emission both falling in the NIR region, have attracted wide attention due to their deep-tissue penetration, high signal-to-noise ratio, and high imaging resolution. The current NIR-NIR bioprobes focused mainly on the 1.5 µm emission of Er3+. Here, we developed a novel bioprobe utilizing the 1.8 µm emission of Tm3+ upon 0.8 µm excitation. After an inert shell effectively suppressing the surface quenching effect, the strong cross relaxation 3H4 + 3H6 → 3F4 + 3F4 between heavily doped Tm3+ greatly improves the luminescence intensity at 1.8 µm. As a result, the formed Tm3+ based NIR-III bioprobe exhibits better penetration ability of the state-of-the-art Er3+ based NIR-III bioprobe, and holding an even larger Stokes shift beneficial for the multiplexed bioimaging and labeling applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
