Titanium silicate molecular sieve, TS-1, catalysed C–C bond formation in Mukaiyama type aldol reactions

Abstract

The titanium silicate molecular sieve, TS-1, efficiently catalyses the formation of carbon–carbon bond in the Mukaiyama type aldol reaction of silyl enol ethers and aldehydes forming β-hydroxy esters/aldols in high yields under heterogeneous and ambient reaction conditions.