Abstract
Tissue healing was compared after apicectomy and filling of ferret lower canines with glass ionomer (Ketacfil) or gutta-percha/sealer (Tubliseal). Both materials provoked an inflammatory response after 7 days, but the response to glass ionomer was less severe. The response after 28 days was different. Mild inflammation related to the gutta-percha was still present, but no inflammation was found in relation to the glass ionomer. Bone infill was quite advanced in all specimens at 28 days but was more complete in the glass ionomer specimens, with intimate contact between the bone and cement.
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