Abstract

From the contents:Cellular and molecular biology of fibroblast and myofibroblast. Some historical and philosophical reflections on the myofibroblast concept. Transcription regulation of the desmin and SM22 genes in vascular concept. Modulation of myofibroblast and smooth muscle phenotypes in the lung. Role of platelet-derived growth factors in angiogenesis and alveogenesis. TGFB gene transfer to the lung induces myofibroblast presence and pulmonary fibrosis.

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