Abstract

Tissue-like P systems with channel states are a type of classical membrane systems in which objects transferred among regions are controlled by states placed in the channels between regions. However, an important biological fact is the existence of a “barrier” to the diffusion of signal molecules, which tend to remain confined to some particular micro-habitat. This feature allows quorum sensing to convey information about the physiological state of spatially separated sub-populations. Therefore, in this article, we design a novel class-variant of P systems named <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">tissue P systems with states in cells</i> (TSIC P systems). Here, each cell contains one and only one state at any moment (the environment has no state), and objects transferred among regions are controlled by states (or a state) that are placed in the corresponding cells (or a cell). We discuss the <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">computability theory</i> of TSIC P systems by showing that Turing universality is acquired by TSIC P systems, which are worked both in a flat maximal parallelism and in a maximal parallelism. In addition, when cell division is considered in TSIC P systems, then tissue P systems with states in cells and cell division (TSICD P systems) are constructed. The (presumed) <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">computational efficiency</i> of TSICD P systems is reached by offering a uniform solution to the satisfiability problem.

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