Abstract
Objective To investigate the value of left ventricular systolic function in patients with pre-apical hypertrophic cardiomyopathy (PAHCM) by tissue motion tracking of mitral annular displacement (TMAD). Methods 26 cases in each group of PAHCM, hypertensive left ventricular hypertrophy (HLVH) and healthy volunteers were selected respectively. All of the subjects were examined by conventional echocardiography and store two-dimensional image of corresponding section. Using biplane Simpson method to measure left ventricular end-diastolic volume (EDV), left ventricular end-systolic volume (ESV) , stroke volume(SV) and left ventricular ejection fraction (LVEF). Mitral annulus systolic peak displacement (SD) and average peak displacement of six sites in three sections were automatic measured in QLAB 9.1 workstation. Results Compared with the control group, the difference was statistically significant at all points of SD and the average peak displacement in PAHCM group [(10.16±1.17) mm vs (13.09±1.25) mm, (9.03±1.35) mm vs (12.45±1.61) mm, (10.25±1.07) mm vs (12.53±1.29) mm, (10.54±1.01) mm vs (12.39±1.52) mm, (9.25±1.13) mm vs (13.09±1.75) mm, (9.95±0.83) mm vs (12.35±0.94) mm, (9.86±0.39) mm vs (12.65±0.68) mm, t=-8.74, -8.98, -6.92, -5.19, -9.37, -9.74, -18.02, P 0.05]. Compared with the control group, the difference was statistically significant at all points of SD and the average peak displacement in HLVH group [ (8.42±1.28) mm vs (13.09±1.25) mm, (8.30±1.27) mm vs (12.45±1.61) mm, (8.36±1.20) mm vs (12.53±1.29) mm, (8.84±1.08) mm vs (12.39±1.52) mm, (8.52±1.21) mm vs (13.09±1.75) mm, (8.58±1.09) mm vs (12.35±0.94) mm, (8.50±0.46) mm vs (12.65±0.68) mm, t=-13.27, -10.34, -12.09, -9.71, -10.93, -13.35, -25.59, P<0.05]. Conclusion Compared with LVEF in PAHCM patients, using TMAD to measure mitral annular systolic displacement, which reflect the changes of left ventricular systolic function, is a more simple and sensitive new method. Key words: Echocardiography; Pre-apical hypertrophic cardiomyopathy; Mitral annular displacement; Ventricle, Left; Systolic function
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