Abstract
Accurate continuous direct measurement of the blood pressure is currently available thru direct invasive methods via intravascular needles, and is mostly limited to use during surgical procedures or in the intensive care unit (ICU). Non-invasive methods that are mostly based on auscultation or cuff oscillometric principles do provide relatively accurate measurement of blood pressure. However, they mostly involve physical inconveniences such as pressure or stress on the human body. Here, we introduce a new non-invasive mechanism of tissue-informative measurement, where an experimental phenomenon called subcutaneous tissue pressure equilibrium is revealed and related for application in detection of absolute blood pressure. A prototype was experimentally verified to provide an absolute blood pressure measurement by wearing a watch-type measurement module that does not cause any discomfort. This work is supposed to contribute remarkably to the advancement of continuous non-invasive mobile devices for 24-7 daily-life ambulatory blood-pressure monitoring.
Highlights
Accurate continuous direct measurement of the blood pressure is currently available thru direct invasive methods via intravascular needles, and is mostly limited to use during surgical procedures or in the intensive care unit (ICU)
Direct measurement of the blood pressure is possible through the electronic pressure transducer in an intravascular cannula needle inserted into a vein
Y’s peak-topeak amplitude, DY is normally proportional to the strength of the radial pulse wave. With these values of DY and Yavg, it can measure only the external applied pressure Ppress and the radial pulse wave delivered to the skin (Y), not the absolute blood pressure inside the radial artery (X)
Summary
Accurate continuous direct measurement of the blood pressure is currently available thru direct invasive methods via intravascular needles, and is mostly limited to use during surgical procedures or in the intensive care unit (ICU). Non-invasive methods that are mostly based on auscultation or cuff oscillometric principles do provide relatively accurate measurement of blood pressure. ABPM devices are mostly based on auscultation[5] or cuff oscillometry[6] principles, both of which can be classified as occlusive technologies[7] that use cuffs, and are non-continuous and originally devised by Korotkoff Some drawbacks of these occlusive methods include petechiae, bruising, and even sleep disorders. In this paper, a new continuous blood pressure monitoring method, based on a newly discovered phenomenon and hypotheses, was proposed for continuous non-invasive ABPM (CNIABPM) that does not produce any discomfort or require the use of any cuffs. Through a prototype implementation and its measurement, the proposed method was verified to achieve meaningful accuracy correlation with respect to a validated commercial device
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