Tissue hydrogen ion concentration in ischemic muscle: Effects of gradual and acute arterial occlusion, with and without acute venous hypertension

Abstract

Accurate assessment of extremity &hernia is often a prerequisite to the successful completion of complex arterial reconstructions. Muscle surface pH, reflecting the status of local tissue metabolism, offers a means for continuously monitoring limb perfusion. The present investigation was designed to evaluate muscle surface pH measurements in ischemic canine hindlimbs. These measurements, subjected to careful statistical analysis, were related to extremity blood flow, perfusion pressure, effluent blood pH, and arteriovenous oxygen differences.