Tissue Engineering in Periodontal Regeneration

Abstract

Periodontal diseases have become exceedingly widespread, and management of the defects due to periodontitis has been a great challenge in periodontal therapies. In the last two decades, concerted efforts have aimed to improve periodontal tissue regeneration by bone grafting and guided tissue regeneration. Recent studies have focused on tissue engineering (TE) techniques for periodontal regeneration using stem cells, growth factors, and scaffolds to grow new functional tissues, rather than building replacements for lost periodontal tissues. The future of periodontal regeneration research requires an understanding of current findings, which in turn highlights the need for future research. In this chapter, we review recent progress in periodontal tissue regeneration and current tissue engineering approaches. The advantages and disadvantages of this method in clinical practice will be also discussed based on recent studies.