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Abstract
A 3D woven fiber scaffold infiltrated with an interpenetrating network hydrogel mimics the load-bearing and tribological properties of native cartilage. The woven fiber scaffold, created by X. Zhao, F. Guilak, and co-workers on page 5833, provides controlled tensile and compressive mechanical properties in three dimensions, while the infused hydrogel, consisting of an interpenetrating network of alginate and polyacrylamide, provides high toughness and a low coeffecient of friction. This biomimetic, fiber-reinforced composite structure has potential as an acellular or cell-based replacement for cartilage.
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