Abstract
The ability to transaminate and decarboxylate [ i- 14C]leucine is widely distributed in guinea pig tissue and is present early in fetal life. The peripheral white blood cell in the human can also transaminate and decarboxylate [ i- 14C]leucine, but the red blood cell, placenta and adult muscle can not. Using sodium α-[ i- 14C]ketoisovalerate as substrate, placental mitochondria and muscle homogenate produced only minimal amounts of decarboxylation of questionable significance. Fractionation of guinea pig liver revealed the cytoplasmic decarboxylase activity to be concentrated in the mitochondrial fraction.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
