“Tiryaq Arba” (a Polyherbal Unani Formulation) as Prophylactic Medicine Against Epidemics of Acute Respiratory Viral Infections

Abstract

: “Tiryaq Arba” is a polyherbal Unani formulation in a majoon dosage form that contains four herbal ingredients, namely habbul ghar (Laurus nobilis), juntiyana romi (Gentiana lutea), murr maki (Commiphora myrrha), and zarawand taweel (Aristolochia longa). The medicine has been used as an antidote against different poisons and as a prophylactic medicine before and/or during epidemics. The constituents have been proposed to act as anti-infective, anti-microbial, and antidote against various infectious agents during epidemics (waba). Scientific experimentation of the above-mentioned constituents has also reinforced their beneficial antiviral, immunomodulatory, and antioxidant properties against epidemics of acute respiratory viral infections such as; severe acute respiratory syndrome coronavirus (SARS-CoV), adenovirus, influenza and influenza A virus, respiratory syncytial virus infections, parainfluenza virus, human rhinovirus B, coxsackievirus, parainfluenza virus type 3, Newcastle disease virus, and influenza A virus, which are a greater cause for morbidity and mortality faced by the world, earlier and at present.