Abstract

Background: There are no current guidelines on the timing of resuming nocturnal non-invasive positive pressure ventilatory therapy after skull base surgery. In patients with obstructive sleep apnea (OSA) undergoing either open or endoscopic skull base surgery, an analysis of risk factors and timing of postoperative cerebrospinal fluid (CSF) leaks would provide important prognostic information and may help clinicians determine when to restart continuous positive airway pressure (CPAP) therapy. There are case reports of CSF leaks and symptomatic pneumocephalus after resumption of CPAP postoperatively, but these appear to be rare although serious events.1,2

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