Abstract

Synthetic endometrial preparation during single euploid embryo transfer (SEET) cycles utilizes sequential estrogen and progesterone (P4) that mimics the natural window of implantation. A concern for synthetic cycles is the possibility of breakthrough ovulation and the inability to suppress follicular growth. Patients undergo close monitoring of the P4 levels to ensure optimal synchronization of endometrial lining and embryo transfer. However, little research has evaluated the duration between P4 level check and initiation of exogenous P4 in frozen embryo transfer (FET) cycles.

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