Abstract
A comparison between early and late ligation of the umbilical cord of 190 premature infants, held on their mother's abdomen after birth, showed no statistically significant differences in the two groups studied with regard to the incidence of respiratory distress syndrome or mortality from hyaline membrane disease. We have concluded from this study that factors other than those proposed by Bound, Harvey, and Bagshaw,1 Moss, Duffie, and Fagan,3 and Taylor, Bright, and Birchard5 must play a more significant role in the pathogenesis of respiratory distress syndrome and the development of pulmonary hyaline membranes in newborn infants.
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