Abstract
Methods Sedated cardiac MRI was performed on a 1.5 T Siemens Sonata. After IV injection of 0.2 mmol/kg of gadolinium (Magnovist), scout images were obtained at 2, 3, 4 and 10 minutes, and turboFLASH PSIR were obtained using standard views at 5-9 minutes. All images were assessed according to a grading score: 0 = none; 1 = reverse; 2 = poor; 3 = partial; and 4 = good nulling. The inversion time (TI) was determined from the best nulled scout image. Images were analysed by 3 independent observers blinded to the clinical information. The mean and standard deviation of the grading score was analysed using the KruskalWallis analysis and interobserver variability was determined by quadratic weighted kappa statistics.
Highlights
Current protocols for late enhancement imaging using adult techniques do not achieve adequate nulling in children
We hypothesize that the timing for late enhancement imaging in adults is not applicable to children
The aim of this study was to determine the best timing for late enhancement imaging in anesthetised children
Summary
Current protocols for late enhancement imaging using adult techniques do not achieve adequate nulling in children. We hypothesize that the timing for late enhancement imaging in adults is not applicable to children. The aim of this study was to determine the best timing for late enhancement imaging in anesthetised children. The anatomy in congenital heart disease (n = 7) or function in cardiomyopathy (n = 5). There was good agreement between observers for scout images at 2 (κ = 0.69) & 3 (κ = 0.66) minutes and a moderate agreement at 4 min (κ = 0.57). Agreement of PSIR images was moderate at 7 min (κ = 0.44) and poor-fair at other times. The mean increase in TI from the 4-10 min scout was 50 ± 15 msec.
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