Abstract
Computer assistance enables the analytical chemist to process data more reliably, efficiently, and expeditiously. The use of the time-sharing computer for this purpose has proved significantly advantageous in our small research-oriented laboratory. The APL time-sharing computer software is described as typically exemplified in the development and recent collaborative study of the GLC assay of griseofulvin. This discussion focuses principally on the processing of the data post-acquisition, and presentss APL as an interactive communication system for data reduction and subsequent formating of output on hard copy. This includes examples of its application with linear regression and plotting of standards, performance requirements of columns, assay determinations by comparison with standards, confidence limits of the mean and various statistical treatments for the evaluation of individual and collective data from the participants of the collaborative study, and a brief critique of the system.
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