Abstract
ObjectiveTo analyze changes in the incidence, diagnostic procedures, comorbidity, length of hospital stay (LOHS), costs and in-hospital mortality (IHM) for patients with bronchiectasis who were hospitalized in Spain over a 10-year period.MethodsWe included all admissions for patients diagnosed with bronchiectasis as primary or secondary diagnosis during 2004–2013.Results282,207 patients were admitted to the study. After controlling for possible confounders, we observed a significant increase in the incidence of hospitalizations over the study period when bronchiectasis was a secondary diagnosis. When bronchiectasis was the primary diagnosis we observed a significant decline in the incidence. In all cases, this pathology was more frequent in males, and the average age and comorbidity increased significantly during the study period (p<0.001). When bronchiectasis was the primary diagnosis, the most frequent secondary diagnosis was Pseudomonas aeruginosa infection. When bronchiectasis was the secondary diagnosis, the most frequent primary diagnosis was COPD. IHM was low, tending to decrease from 2004 to 2013 (p<0.05). The average LOHS decreased significantly during the study period in both cases (p<0.001). The mean cost per patient decreased in patients with bronchiectasis as primary diagnosis, but it increased for cases of bronchiectasis as secondary diagnosis (p<0.001).ConclusionsOur results reveal an increase in the incidence of hospital admissions for patients with bronchiectasis as a secondary diagnosis from 2004 to 2013, as opposed to cases of bronchiectasis as the primary diagnosis. Although the average age and comorbidity significantly increased over time, both IHM and average LOHS significantly decreased.
Highlights
Bronchiectasis is characterized by abnormal and irreversible bronchial dilation, with ciliary epithelium dysfunction as a consequence of clinical pathology that includes respiratory infection, chronic inflammation and mucociliary system lesions [1]
Our results reveal an increase in the incidence of hospital admissions for patients with bronchiectasis as a secondary diagnosis from 2004 to 2013, as opposed to cases of bronchiectasis as the primary diagnosis
The average age and comorbidity significantly increased over time, both in-hospital mortality (IHM) and average length of hospital stay (LOHS) significantly decreased
Summary
We included all admissions for patients diagnosed with bronchiectasis as primary or secondary diagnosis during 2004–2013. After controlling for possible confounders, we observed a significant increase in the incidence of hospitalizations over the study period when bronchiectasis was a secondary diagnosis. When bronchiectasis was the primary diagnosis we observed a significant decline in the incidence In all cases, this pathology was more frequent in males, and the average age and comorbidity increased significantly during the study period (p
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