Time trend of breast cancer mortality in BRAZILIAN men: 10-year data analysis from 2005 to 2015

Jean Henri Maselli-Schoueri,Francisco Winter Dos Santos Figueiredo,Fernando Alves Affonso-Kaufman,Claudia Vaz De Melo Sette,Fernando Adami

doi:10.1186/s12885-018-5261-1

Jean Henri Maselli-Schoueri, Francisco Winter Dos Santos Figueiredo + Show 3 more

Open Access

https://doi.org/10.1186/s12885-018-5261-1

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Journal: BMC Cancer	Publication Date: Jan 7, 2019
Citations: 2	License type: open-access

Affiliation: Faculdade de Medicina do ABC

Abstract

BackgroundMale Breast Cancer (MBC) is rare, which makes its understanding and treatment be extrapolated from what is known about the occurrence in women, with few epidemiological studies. Therefore, the aim of the present paper was to study breast cancer mortality in adult males in Brazil and its administrative regions between 2005 and 2015.MethodsEcological study with data on MBC mortality in adults between 2005 and 2015. Data were obtained from the Mortality Information System of the Department of Informatics of SUS (the Unified Health System of the country). Descriptive statistics were used for MBC mortality and linear regression to analyze the relationship between mortality and the country’s administrative regions. Percentage Change (PC) and Annual Percentage Change (APC) were the trend measures used for MBC mortality for the period.ResultsBetween 2005 and 2015, there were 1521 deaths due to MBC in adults in Brazil. Regarding mortality by region, there was great oscillation in the rates of the country as a whole (PC = 113,87; β = 0,009 (IC95% 0,000 – 0,018); r2 = 0,381; P = 0,043). The highest increase in MBC mortality occurred in patients aged 80 years or older (PC = 161,04; β = 0,201 (IC95% 0,640 - 0,339); r2 = 0,550; P = 0,009) and there was significant increase in deaths for the 50–54-year age group (PC = 224,01; β = 0,135 (CI95% 0,052; 0,218); r2 = 0,601; P = 0,005).ConclusionMortality in adults due to MBC increased in Brazil during the study period with the highest percentage increase occurring for individuals aged 80 years or older.

Highlights

Male Breast Cancer (MBC) is rare, which makes its understanding and treatment be extrapolated from what is known about the occurrence in women, with few epidemiological studies
Regarding the variation of the mortality rates for Brazil, there was a great oscillation during the period as a whole, the annual variation being small (β = 0,009 (CI 95% 0,0001; 0,018); r2 = 0,396; P = 0,038) (Fig. 1)
In spite of the high values found in mortality rates variation throughout the period - represented by the high Annual Percentage Change (APC) values - the analysis of each region separately did not present any statistically significant results (P > 0,05) (Table 1)

Summary

Introduction

Male Breast Cancer (MBC) is rare, which makes its understanding and treatment be extrapolated from what is known about the occurrence in women, with few epidemiological studies. The aim of the present paper was to study breast cancer mortality in adult males in Brazil and its administrative regions between 2005 and 2015. In Brazil, it is a public health problem [3] and data suggests it may be worsened by differences in income between populations of the country [4]. It is well-known that, in general, the sex of an individual implies differences in susceptibility to cancer [5], resulting in different rates of both incidence and mortality amongst. It is expected for 2017 that roughly 18, 5% of American men diagnosed with Male Breast Cancer (MBC) shall die due to the disease [11].

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