Time to recovery and determinant factors of COVID-19 patients under treatment in Sidama region, Ethiopia: A retrospective cohort study

Abstract

IntroductionEvidence from several studies shows that the median recovery time among COVID-19 patients varies in different settings, and why that difference occurs is questionable. The current study was aimed to estimate the time to recovery and to identify determinant factors among COVID-19 patients admitted to treatment centers in the Sidama region, Ethiopia. MethodsThe secondary data was extracted from the Sidama Public Health Institute (SPHI), data management unit. A total of 1038 COVID-19 patients who were under treatment from 1, June 2020, to 30, June 2022, at different treatment centers in the region were included in the study. The Log-Logistic Accelerated Failure Time (AFT) model was employed to estimate the effects size of different covariates on recovery time of COVID-19 patients under treatment. ResultsAmong the total number of patients in the study, 704 (67.82 %) were recovered, while 334(32.18 %) were censored. The median recovery time was 14 days (IQR: 10–18 days). Patients who were above 65 years old had nearly 1.17 times more prolonged recovery time as compared to patients who were below 25 years old, (OR = 1.168, p-value = 0.032, CI = 0.013,0.298). The log odds of recovery for patients who were in critical severity status at admission was 1.279 times more decelerated as compared to asymptomatic patients (P-value = 0.005, CI = 0.076, 0.417). The log odds of recovery for patients who had no history of headache was 1.107 times more accelerated as compared to patients who had a history of headache (OR = 1.107, p-value = 0.027, CI = 0.011, 0.192). The log odds of recovery for non-diabetic patients was 1.244 times more accelerated as compared to patients who were diabetic (OR = 1,244, p-value = 0.002, CI = 0.077, 0.360), holding other covariates constant in the model. ConclusionAge, critical severity status of infection, having symptoms of infection, having a history of headaches, and being diabetic had statistically significant effects on time to recovery among COVID-19 patients admitted to the treatment centers in the Sidama region.