Abstract

Rationale: Time-restricted feeding, a specific form of intermittent fasting, has been associated with several possible health benefits including improved body composition, blood lipid levels and extended lifespan. However, it is unknown if time-restricted feeding confers a protective effect on the physical function of older adults. The aim of this study was to assess time-restricted feeding in association with performance-based lower-extremity function (LEF) in a large population of community-dwelling older adults.

Highlights

  • Several types of intermittent fasting have emerged as an alternative to caloric restriction and to a prolonged period of fasting because this diet strategy is relatively easy to maintain [1] and there is some evidence from studies in animals and humans that it might improve overall health [2] and body composition [3], protects against cardiometabolic risk factors [4, 5], and extends life span [6]

  • Time-restricted feeding was associated with a higher likelihood of impaired lower-extremity function (LEF), balance impairment, and difficulty to rise from a chair in older adults

  • Fasting time showed a significant association with balance impairment (OR for longest vs. shortest fasting time: 2.48; 95% confidence intervals (CI): 1.51-4.08; p-trend= 0.001) and difficulty to rise from a chair

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Summary

Introduction

Several types of intermittent fasting have emerged as an alternative to caloric restriction and to a prolonged period of fasting because this diet strategy is relatively easy to maintain [1] and there is some evidence from studies in animals and humans that it might improve overall health [2] and body composition [3], protects against cardiometabolic risk factors [4, 5], and extends life span [6]. A specific type of intermittent fasting is time-restricted feeding (TRF), in which the daily eating period is limited to 12 hours or less per day. Time-restricted feeding, a specific form of intermittent fasting, has been associated with several possible health benefits including improved body composition, blood lipid levels and extended lifespan. It is unknown if time-restricted feeding confers a protective effect on the physical function of older adults. The aim of this study was to assess time-restricted feeding in association with performance-based lower-extremity function (LEF) in a large population of community-dwelling older adults

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