Abstract

Neuroscience In studies of human behavior, current models of response inhibition, the ability to suppress a natural impulse or response, assume that “stop” and “go” processes independently race against each other, and the “winner” determines whether the unwanted response is stopped. Bissett et al. analyzed nearly a million trials from a response inhibition paradigm commonly used in psychology, psychiatry, and neuroscience. The independence assumption did not hold, and this failure influenced key dependent variables. The violation occurred for fast and slow subjects, for manual responses and saccadic eye movements, and for visual and auditory stimuli. New models are needed to improve the theoretical foundations of response inhibition. Sci. Adv. 10.1126/sciadv.abf4355 (2021).

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