Abstract

This study compared the demineralization resistance of teeth treated with silver diamine fluoride (SDF) to that treated with fluoride varnish. A total of 105 healthy bovine incisors were divided into control, fluoride varnish, and SDF groups. The enamel surface density change was then measured by micro-computed tomography (micro-CT) at three depths. The demineralized zone volume was measured on 3D micro-CT images to evaluate the total demineralization rate. The enamel surface morphology was assessed by scanning electron microscope. The enamel density had continuously decreased while demineralization increased in the control and fluoride varnish groups. The enamel density had increased in the SDF group till the 7th day of demineralization treatment and decreased thereafter. However, the decrease in the SDF group was less severe than that in the other groups (p < 0.05). The demineralized enamel volume had increased through treatment and was the highest in the control group, followed by the fluoride varnish and SDF group. The enamel surface morphology was the roughest and most irregular in the control group, followed by the fluoride varnish group and SDF groups.

Highlights

  • Dental caries is a biofilm-mediated, diet modulated, multifactorial, non-communicable, dynamic disease resulting in net mineral loss of dental hard tissues [1]

  • We examined the change in density and demineralization volume by assessing the enamel surface and depth using scanning electron microscopy (SEM) and micro-CT

  • The density of the control and MI VarnishTM groups continuously declined; the decrease was greater in the control group

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Summary

Introduction

Dental caries is a biofilm-mediated, diet modulated, multifactorial, non-communicable, dynamic disease resulting in net mineral loss of dental hard tissues [1]. The prevalence rate that headed for a rapid decline by the 2000s is no longer declining and is increasing rapidly in some countries. This phenomenon is more prominent in early childhood caries (ECC) [2]. According to the children’s oral health status in South Korea, dental caries experience rate in the deciduous teeth of 5-year-old children declined from 82% in 1995 to 61.5% in 2010, but has risen to 64.4% in 2015. The most widely used prophylaxis for dental caries, has a remineralizing effect and increases the acid resistance of enamel. The anti-cariogenic effect of fluoride varnish was found to be incomplete

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