Abstract

We examined the relationship between levels of exercise intensity and 3 markers of oxidative stress(expired ethane and pentane, and serum malonaldehyde[MDA]). Seven healthy men and women(age = 36.4 ± 8 years[mean ± SD) underwent cardiopulmonary physical exercise stress testing to VO2MAX. We measured levels of expired ethane and pentane: before exercise; at anaerobic threshold(A.T.); at peak exercise(VO2MAX= 56.6 ± 7 ml/kg/Min); and 5 minutes post exercise. Resting serum MDA levels were drawn before and after exercise. Table The results of expired ethane and pentane indicate that, in healthy individuals, substantial exercise-induced oxidative stress occurs at A.T. and continues to increase to VO2MAX, yet it rapidly attenuates during post- exercise recovery. Levels of serum MDA, a marker of cumulative oxidative stress, is not affected by exercise. These findings indicate that healthy individuals are protected from exercise-induced-oxidative-stress.

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