Abstract
Purpose To assess the simulated keratometry (Sim K) and the total corneal refractive power (TCRP) in eyes undergoing conventional corneal cross-linking (CXL). Methods This study comprised 20 eyes of 20 keratoconic patients (14 men and 6 women; median age (25th and 75th percentile), 26.5 (21.8, 38.0) years) who underwent CXL. The Sim K and TCRP were measured with a rotating Scheimpflug system (Pentacam HR, Oculus), preoperatively and 1, 3, 6, and 12 months postoperatively. Results The values of Sim K were 52.65 (46.00, 55.70), 52.45 (45.85, 56.88), 51.70 (45.78, 55.83), 51.40 (45.68, 56.80), and 51.25 (46.08, 56.15) D preoperatively and 1, 3, 6, and 12 months postoperatively, respectively. The corresponding figures of TCRP were 52.10 (45.48, 55.08), 51.30 (45.18, 55.20), 50.95 (45.15, 54.50), 50.00 (45.18, 55.08), and 49.80 (45.48, 54.15) D, respectively. The variances of the Sim K and TCRP data were not statistically significant (p=0.994 and p=0.970, respectively, Kruskal–Wallis test). The Sim K was significantly larger than the TCRP before CXL and at 1, 3, 6, and 12 months after CXL (p<0.001, Wilcoxon signed-rank test). Conclusions Not only the Sim K but also TCRP was decreased by approximately 1 D after CXL. The Sim K readings may overestimate the TCRP, even after CXL for progressive keratoconus.
Highlights
Keratoconus is a progressive noninflammatory disorder characterized by anterior protrusion and thinning of the cornea, deteriorating visual performance with time
We usually evaluated the progression of the disease mainly in terms of the keratometric readings obtained by using a corneal topographer or a autokeratometer, both of which were routinely used in daily practice
To the best of our knowledge, the time course of changes in the true corneal power has not so far been extensively investigated in eyes having CXL treatment. It may give us intrinsic insights into the precise changes in the true corneal power, which are essential to determine the precise intraocular lens (IOL) power and/or rigid gas permeable (RGP) lens power in such patients in daily practice
Summary
Keratoconus is a progressive noninflammatory disorder characterized by anterior protrusion and thinning of the cornea, deteriorating visual performance with time. We usually evaluated the progression of the disease mainly in terms of the keratometric readings obtained by using a corneal topographer or a autokeratometer, both of which were routinely used in daily practice. These keratometric readings are theoretically calculated based on the assumption that the ratio of the anterior and posterior curvatures remained constant. To the best of our knowledge, the time course of changes in the true corneal power has not so far been extensively investigated in eyes having CXL treatment It may give us intrinsic insights into the precise changes in the true corneal power, which are essential to determine the precise intraocular lens (IOL) power and/or rigid gas permeable (RGP) lens power in such patients in daily practice. The purpose of the current study is to retrospectively assess the time course of changes in the Sim K and TCRP, in a cohort of progressive keratoconic subjects who underwent conventional CXL treatment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
