Abstract

Lithium hydroxybutyrate has a broad spectrum of action and exhibits its activity in widely different pathological states [2]. The writers showed previously [I] that this compound, if given prophylactically, inhibits the development of peritonitis in rats caused by intraperitoneal injection of silver nitrate, and edema of the limbs caused by subplantar injection of biologically active substances which are mediators of inflammation. One of the most important criteria for evaluation of the compound as an anti-inflammatory agent is its ability to inhibit the development of carrageenin inflammation [8].

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