Abstract
Inspiratory unloading decreases ventilatory drive and work of breathing in patients undergoing mechanical ventilation. We examined the time course of this effect in patients receiving permanent ventilatory support, provided by pressure support ventilation (PSV), or intermittent ventilatory support, provided by biphasic positive airway pressure (BIPAP).
Highlights
Lipopolysaccharides (LPS) are known to be involved in the pathogenesis of septic shock and multiorgan failure
Prospective, longitudinal, descriptive cohort study with no therapeutic interventions in which participated 63 patients admitted to the intensive care unit (ICU) with the clinical diagnosis of severe sepsis (21) or septic shock (42) [3] and 10 healthy adults that served as controls
This study shows for the first time that preoperative measurement of C-reactive protein (CRP) may offer a useful, predictive marker in risk stratification for postoperative infections in patients scheduled for cardiac surgery
Summary
Lipopolysaccharides (LPS) are known to be involved in the pathogenesis of septic shock and multiorgan failure. Conclusions: The combination of these two new and not very well known techniques, TGI and BIPAP, were useful in avoiding the adverse effects of high pressures and volumes to counteract the effects of high arterial CO2 levels in patients with limited cardio-circulatory status and acute or chronic lung and cerebral diseases In this small sample, considering the influence of time in the reduction of PACO2 and in the increase of pH values, the best moment to verify the response of TGI is beyond 60 min. Methods: 24 critically ill, MV patients (mean APACHE II score: 21, mean age 64 ± 14 yrs, 15 men), hospitalized in a medical intensive care unit, were prospectively included for 24-h esophageal pH and duodenogastroesophageal reflux (DGER) studies (Digitrapper III pH-meter and fiber-optic sensor for the presence of bilirubin, Bilitec 2000, Synectics, Sweden) with single sensors placed 5 cm proximal to the lower esophageal sphincter (LES) and instrumented with a nasogastric tube. Discussion and conclusion: The comparisons between institutions must be corrected for several factors: variations in casemix, patients co-morbidites, status of previous disease, delays in referral, social factors and access to
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
