Abstract
Thrombocytopenia is a common laboratory finding among critically ill patients. Studies have shown that thrombocytopenia is associated with increased morbidity and mortality, however there is limited evidence showing increasing mortality with increasing severity of thrombocytopenia. Several risk factors, such as sepsis and surgery, have been associated with thrombocytopenia. The relationship between routine coagulation parameters and platelet count has not been explored.
Highlights
Thrombocytopenia is a common laboratory finding among critically ill patients
The relationship between routine coagulation parameters and platelet count has not been explored. This retrospective study included Intensive Care Unit (ICU) patients admitted to the Royal Liverpool University Hospital between January 2008- January 2012
Severely thrombocytopenic patients had an increased morbidity and mortality in this large cohort study. They took longer for improvement in platelet count and are linked with poor outcomes
Summary
Thrombocytopenia is a common laboratory finding among critically ill patients. Studies have shown that thrombocytopenia is associated with increased morbidity and mortality, there is limited evidence showing increasing mortality with increasing severity of thrombocytopenia. Several risk factors, such as sepsis and surgery, have been associated with thrombocytopenia. The relationship between routine coagulation parameters and platelet count has not been explored
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