Abstract
Acute pancreatitis is an inflammatory event of the pancreas which may affect seriously all other tissues and organ systems. Generally, acute pancreatitis is induced by alcoholism or gallstones. However pathogenetic mechanisms of drug induced pancreatitis are not clearly understood. A minocycline derivative, tigecycline is a glycylcycline class of antibiotic which is structurally similar to the tetracyclines. It has perfect tissue and organ distribution and favorable microbial coverage, including many kind of Gram-positive and Gram-negative bacteria and also anaerob agents. Tigecycline’s side-effect profile is similar to the tetracyclines. Pancreatitis is a well-known adverse effect of tetracyclines. However, tigecycline-induced pancreatitis is an uncommon side-effect. We report here a rare case of tigecycline-induced pancreatitis during the treatment of a diabetic food infection.
Highlights
Acute pancreatitis is an inflammatory event of the pancreas which may affect seriously all other tissues and organ systems [1,2,3]
A 64-year-old man was admitted to hospital because of diabetic food infection requiring glisemic control and antibiotheraphy
Tigecycline is a globally used wide spectrum antibiotic which is used for many kinds of infectious circumstances [8]
Summary
Acute pancreatitis is an inflammatory event of the pancreas which may affect seriously all other tissues and organ systems [1,2,3]. A 64-year-old man was admitted to hospital because of diabetic food infection requiring glisemic control and antibiotheraphy. He had a history of cholecystectomy operation nearly 5 years ago. His medical history consisted of no alcohol consumption for five years.
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